Edorium Journal of

Respiratory Medicine

 
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Case Report
 
Nodular pulmonary light chain deposit disease: An unexpected finding on histology
Muazzam Tahir1, Sean Galvin2
1MBBS, Wellington Regional Hospital, registrar cardiothoracic surgery, cardiothoracic department, Wellington Regional Hospital, Wellington, New Zealand.
2FRACS, Wellington Regional Hospital, Consultant surgeon cardiothoracic surgery, cardiothoracic department, Wellington Regional Hospital, Wellington, New Zealand.

Article ID: 100002R05MT2016
doi:10.5348/R05-2016-2-CR-1

Address correspondence to:
Muazzam Tahir
Flat no 504, 20 Hanson Street, Mount Cook
Wellington
New Zealand

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How to cite this article
Tahir M, Galvin S, Nodular pulmonary light chain deposit disease: An unexpected finding on histology. Edorium J Respir Med 2016;2:1–3.


Abstract
Introduction: Nodular pulmonary light chain deposit disease is a rare histological diagnosis which can be associated with poor outcome.
Case Report: A 73-year-old male was incidentally found to have two pulmonary nodules. Histology following resection confirmed nodular pulmonary light chain deposit disease, a rare condition. He was subsequently found to have multiple myeloma.
Conclusion: Pulmonary light chain deposit disease has two forms namely diffuse and nodular. Diffuse form has poor prognosis and nodular is associated with lymphoproliferative and/or plasma cell dyscrasia in half of the patients, hence early diagnosis is crucial.

Keywords: Immunoglobulin light chain, Kappa, Lambda, Light chain deposition disease, Pulmonary nodule


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Author Contributions
Muazzam Tahir – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Sean Galvin – Substantial contributions to conception and design, Acquisition of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2016 Muazzam Tahir et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.



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